Parliament of Australia:Senate:Committees:Community Affairs Committee:Breaking the silence: a national voice for gynaecological cancers

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Appendix 3 - NHMRC funding for gynaecological cancer in Australia – 2000-2006

Program Grants (3)

Researcher	Institution	Project Title	Duration	Total Funding
Prof David de Kretser	Monash University	Control of reproductive processes	2000	$4,322,218
Dr Georgia Chenevix-Trench	Queensland Institute of Medical Research	Towards an understanding of the genetic basis of breast and ovarian	2003-2007	$4,284,405
Prof Adele Green	Queensland Institute of Medical Research	Towards cancer control: Population and molecular strategies	2002-2006	$5,411,880
			TOTAL	$14,018,503

Project Grants (51)

Researcher	Institution	Project Title	Duration	Total Funding
Prof Francis J Bowden	Australian National University	Screening for Chlamydia trachomatis with routine Pap smears in general practice: A randomised controlled trial	2005-2007	$350,500
A/Pr Roger J Daly	Garvan Institute of Medical Research	Regulation of mitogenic signalling via the Gab2 docking protein	2003	$141,750
Prof Judith M Lumley	La Trobe University	Perinatal outcomes following treatment for cervical dysplasia	2003-2004	$98,600
A/Pr Michael A McGuckin	Mater Misericordiae Health Services Brisbane Limited	The muc1 epithelial mucin in breast and ovarian cancer	2000	$355,548
A/Pr Martin Pera	Monash University	Regulation Of Human Multipotent Stem Cells By Membrane Bound And Soluble Factors	2000-2001	$344,732
A/Pr Peter AW Rogers	Monash University	Regulation of endometrial angiogenesis and lymphangiogenesis	2006-2008	$477,750
A/Prof Peter AW Rogers	Monash University	New blood vessel growth in the human uterus	2000-2004	$744,219
Dr Caroline E Gargett	Monash University	A study of cells responsible for growth of the human uterus	2004-2006	$409,575
Dr Jillian M Shaw	Monash University	Development of ovarian cryopreservation and autografting procedures	2000	$264,367
Prof David A Jans	Monash University	Regulation of nuclear import of viral oncoproteins and transcription factors by protein-protein interactions	2001-2005	$650,383
Prof Donald McNaughton	Monash University	Infrared spectroscopic imaging in the diagnosis of cervical cancer	2003-2005	$291,600
A/Pr Freddy Sitas	NSW Cancer Council	The effect of exogenous hormones, smoking and HPV on the incidence of screen detected pre-invasive cervical cancer	2006-2010	$1,151,625
Prof Mark S Baker	Peter MacCallum Cancer Centre	Understanding ovarian cancer metastasis	2000-2002	$166,725
Prof Peter J Fuller	Prince Henry's Institute of Medical Research	Identification of Key Genes in Cancer of the Ovary	2000-2002	$264,601
A/Pr Andreas Suhrbier	Queensland Institute of Medical Research	A new function for a known enzyme inhibitor- implications for cancer	2004-2006	$463,500
A/Pr Andreas Suhrbier	Queensland Institute of Medical Research	The human papilloma virus oncoprotein E7 degrades the retinoblastoma protein by enhancing calpain activity	2006-2008	$252,500
Dr Amanda B Spurdle	Queensland Institute of Medical Research	Functional Evaluation of BRCA1 & BRCA2 Unclassified Sequence Variants and Identification of Critical Pathogenic Domains	2003-2005	$331,313
Dr Amanda B Spurdle	Queensland Institute of Medical Research	Molecular Epidemiology of Endometrial Cancer	2005-2007	$1,473,480
Dr Georgia A Chenevix-Trench	Queensland Institute of Medical Research	Microarray-targeted candidate gene approach to finding ovarian cancer susceptibility genes	2006-2008	$601,250
Prof Judith Clements	Queensland University of Technology	Expression and functional studies on the novel ovarian-expressed serine protease, Kallikrein 4, in ovarian tumorigenesis	2003-2005	$410,250
Prof Judith Clements	Queensland University of Technology	Role of Kallikreins in ovarian cancer progression	2006-2008	$498,750
Prof Richard Ivell	University of Adelaide	Relaxin signalling in the endometrium and the regulation of early pregnancy	2005-2007	$466,125
A/Pr Ian G Campbell	University of Melbourne	Cloning of chromosome 22 tumour suppressor genes	2004-2006	$249,250
A/Pr Ian G Campbell	University of Melbourne	LOH in cancer associated stroma	2006-2008	$392,500
A/Pr Ian G Campbell	University of Melbourne	Genome-wide study of loss of heterozygosity using high density SNP arrays to identify breast cancer predisposition genes	2006-2008	$531,250
A/Pr Wayne A Phillips	University of Melbourne	Phosphatidylinositol 3-kinase mutations associated with ovarian, colon and breast tumour	2004-2005	$154,000
A/Pr Wayne A Phillips	University of Melbourne	PI 3-kinase: a new player in human cancer	2006-2008	$542,750
Dr Phillip K Darcy	University of Melbourne	Activation and expansion of gene-engineered killer T cells	2002	$115,660
Dr Richard B Pearson	University of Melbourne	Biochemical analysis of Akt 3-specific signal transduction	2005-2007	$349,375
Prof David DL Bowtell	University of Melbourne	Molecular Epidemiology of Ovarian Cancer: The Australian Ovarian Cancer Study National Clinical Follow-Up Core	2006-2010	$830,000
Prof David DL Bowtell	University of Melbourne	Combined expression analysis and SNP-based measurement of copy number variation in ovarian cancer	2006-2008	$432,500
Prof Joseph F Sambrook	University of Melbourne	kConFaB - A Consortium for research on familial breast cancer	2000-2002	$1,624,711
Prof Lenore H Manderson	University of Melbourne	Social aspects and cultural meanings of gynaecological cancer diagnosis, treatment and adjustment of Victorian women	2004-2005	$158,500
Dr Bettina Meiser	University of New South Wales	A randomised trial of a decision aid for women at increased risk for ovarian cancer	2002-2003	$115,110
Prof Robyn Ward	University of New South Wales	Germline epimutations of tumour suppressor genes in familial cancer	2005-2007	$502,500
Dr Germain J Fernando	University of Queensland	How to induce a long lasting anti-tumour response	2000-2002	$242,567
Dr Germain J Fernando	University of Queensland	Optimising immunity towards cancers by vaccination	2002-2004	$211,320
Dr Graham R Leggatt	University of Queensland	CTL avidity as a determinant of the mature, antigen-specific immune repertoire	2000-2003	$241,528
Dr Nigel AJ McMillan	University of Queensland	The role of the human papillomavirus in alpha-6 integrin activation and cell growth	2000-2001	$229,217
Dr Nigel AJ McMillan	University of Queensland	NHPV and cervical carcinoma: Signalling and clinical responses to interferons	2002-2004	$534,480
Dr Nigel AJ McMillan	University of Queensland	Treatment of virally-induced cancers by RNA Interference	2004-2006	$389,250
Prof Ian H Frazer	University of Queensland	Determinants of effective immunotherapy for epithelial tumours	2000-2001	$344,432
Prof Ian H Frazer	University of Queensland	How does papillomavirus regulate its late gene expression?	2000-2001	$237,350
Prof Ian H Frazer	University of Queensland	Effective immunotherapy for HPV associated cervical cancer precursor lesions	2002-2004	$482,640
Prof Ian H Frazer	University of Queensland	Immunoregulatory immune responses to a peripherally presented tumour antigen	2003-2005	$219,750
Prof Robert W Tindle	University of Queensland	Immunological consequences of epithelial expression of a viral oncoprotein associated with cervical carcinoma	2000-2001	$192,069
Prof Robert W Tindle	University of Queensland	A cervical cancer vaccine for the out-bred human population	2001-2002	$214,697
Prof Robert W Tindle	University of Queensland	Overcoming immune response non-reactivity in cervical cancer	2001-2004	$212,037
Prof Robert W Tindle	University of Queensland	Improving the efficiency of DNA vaccines	2005-2006	$182,000
A/Pr Christine L Clarke	University of Sydney	Modulation of cytoskeletal structure by progesterone receptor isoforms	2002-2004	$337,650
A/Pr Paul R Harnett	University of Sydney	Certain death in uncertain time: a qualitative study of the experience of advanced ovarian cancer	2006-2008	$217,500
			TOTAL	$20,695,736

Scholarships (16)

Researcher	Institution	Project Title	Duration	Total Funding
Ms Fiona J Bruinsma	La Trobe University	Perinatal outcomes following treatment for cervical dysplasia	2005-2008	$52,121
Ms Kathryn A Morris	La Trobe University	Cancer screening: Is there a coherent ethical framework?	2001-2004	$86,715
Dr Simon Chu	Prince Henry's Institute of Medical Research	Molecular pathogenesis of ovarian tumours	2000-2003	$66,376
Dr Catherine M Olsen	Queensland Institute of Medical Research	Anthropometric indices, physical activity and ovarian cancer: causation, diagnosis and survival	2006-2008	$63,693
Dr Stephen A Myers	Queensland University of Technology	Estrogen and progesterone regulation of tissue kalli- krein gene expression in endometrial cancer cell lines	2000-2002	$56,627
Dr Sally E Baron-Hay	Royal North Shore Hospital	The Role of the Insulin-like Growth factors and their Binding Proteins in the Pathogenesis of Ovarian Cancer	2001-2004	$55,941
Miss Natalie Wray	University of Melbourne	Gynaecological Cancers: A study of the attitudes and experiences of Australian-born and immigrant Middle Eastern women	2001-2003	$47,805
Miss Natalie Wray	University of Melbourne	The attitudes and understandings of women with gynaecological cancer.	2002	$8,900
Miss Wen Qiu	University of Melbourne	Cellular, molecular & genetic characterization of breast & ovarian cancer-associated fibroblasts (CAFs)	2006-2009	$63,693
Miss Chin-Yi Kan	University of New South Wales	Investigating the regions/functions of HPV E6 proteins required for immortalisation of normal cells	2005	$20,484
A/Pr Sherry Wu	University of Queensland	Liposomal delivery of RNA inhibitory nucleotides for treatment of cervical cancer	2006-2008	$80,451
Dr Jennifer Broom	University of Queensland	Optimising immunotherapy for chronic viral infection	2006-2008	$91,800
Dr Elizabeth Davey	University of Sydney	How the prevention of cervical cancer can be improved by new methods of screening and testing	2004-2005	$51,897
Dr Georgina E Hale	University of Sydney	The natural history of the physiological, hormonal, endometrial and ovarian dynamics during the perimenopause: A 3-yr lo	2001-2004	$98,103
Dr Rohini Sharma	University of Sydney	Identification of novel molecular targets for antibody-directed therapy of ovarian cancer	2004-2006	$89,517
Mr Anthony Newall	University of Sydney	A model for evidence based introduction of a new vaccine to Australia - human papillomavirus vaccine	2006-2007	$42,462
			TOTAL	$976,585

Strategic Awards (2)

Researcher	Institution	Project Title	Duration	Total Funding
Prof Joseph F Sambrook	University of Melbourne	Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer	2003-2006	$3,195,990
Prof Ian H Frazer	University of Queensland	Study of HPV 6 L1 virus like particles as Therapeutic vaccine for genital warts and recurrent respiratory papillomatosis.	2004-2008	$615,608
			TOTAL	$3,811,598

Career Awards (7)

Researcher	Institution	Project Title	Duration	Total Funding
A/Pr David Robertson	Prince Henry's Institute of Medical Research	NHMRC Career Awards	2001	$86,574
A/Pr David Robertson	Prince Henry's Institute of Medical Research	NHMRC Career Awards	2002-2006	$683,000
Dr David Whiteman	Queensland Institute of Medical Research	NHMRC Career Awards	2004-2008	$590,250
Dr Georgia Chenevix-Trench	Queensland Institute of Medical Research	NHMRC Career Awards	2002-2003	$235,000
Prof Judith Clements	Queensland University of Technology	NHMRC Career Awards	2006-2010	$701,250
Prof Suzanne Garland	University of Melbourne	NHMRC Career Awards	2005-2009	$386,925
Prof Simon Foote	Walter and Eliza Hall Institute	NHMRC Career Awards	2003-2004	$250,000
			TOTAL	$2,932,999

Training Awards (4)

Researcher	Institution	Project Title	Duration	Total Funding
Dr Penelope L Jeffery	Mater Medical Research Institute	Cell surface mucins modulate epithelial cell growth and apoptosis of normal mucosal wound repair and epithelial cancers	2005-2009	$264,000
Dr Marguerite S Buzza	Monash University	Studies on the role of Testisin in fertility & cancer using knockout mice	2006-2010	$299,856
Dr Rachel E Neale	Queensland Institute of Medical Research	Smoking and Hormonally related cancers: Epidemiological Studies	2003-2007	$330,186
Dr Susan M Shanley	Sydney West Area Health Service	Identification of putative tumour suppressor gene on chromosome 1p36 in breast and ovarian carcinomas	2001-2006	$410,040
			TOTAL	$1,304,082

Fellowship (2)

Researcher	Institution	Project Title	Duration	Total Funding
Dr Wenyi Gu	University of Queensland	Sensitise cervical cancer cells to shRNA-mediated gene silence	2006-2009	$265,250
Dr Kirsten J McCaffery	University of Sydney	Women's understanding of cervical screening and human papillomavirus (HPV): development and evaluation of a decision aid	2001-2004	$251,012
			TOTAL	$516,262

Source: Submission 42, pp.5-11 (NHMRC).

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